According to a study conducted by the Roswell Park Cancer Institute in New York, published in the periodical “PLoS Genetics,” which reveals that fathers may be somewhat responsible for passing genetic risk factors to their daughters, that may trigger for ovarian cancer.
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Further, looking at the cancer patterns within families, researchers have found that women had a higher risk of cancer if their paternal grandmothers were afflicted by the same cancer disease.
The study results that women with a mutation on a particular gene found on the X chromosome, known as MAGEC3, appeared to get cancer approximately 6.7 years earlier than they would have without the mutation.
The study also says that the average age that women with the mutation gene got the cancer was 40 to 44. Source
There is also evidence regarding ovarian cancer through mutation genes such as mutations in genes linked to ovarian cancer risk include BRCA1 and BRCA2.
Women who carry a BRCA1 mutation have up to a 65-70 percent chance of getting ovarian cancer at some point whereas genetic tests exist for BRCA1 and BRCA2, testing could be done for MAGEC3, according to the U.S. American Cancer Society.
The study data also reveals that women born to fathers whose mother had been affected by the cancer were twice as likely to develop the disease, compared to those who inherited the disease from their mother’s side.
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What Actually is an Ovarian Cancer?
Ovarian cancer is a type of cancer that forms in or on an ovary, its results are abnormal cells that have the ability to attack or spread to other parts of the body.
basically, there are several symptoms that may be seen during cancer progress such as bloating, abdominal swelling, pelvic pain, and loss of appetite. Common areas to which cancer may spread are the lining of the abdomen, lungs, lymph nodes, and liver.
What are the Signs & Symptoms of Ovarian Cancer?
Ovarian cancer is one of the most difficult cancer to detect, particularly in the early stages. This is somewhat due to the fact that the ovaries (a tiny almond-shaped female reproductive organ in which eggs or ova are produced, present in humans and other vertebrates as a pair) are deep within the abdominal cavity.
There are often identified signs and symptoms of ovarian cancer including;
- Trouble eating or feeling full quickly
- Pelvic or abdominal pain
- Feeling the need to urinate urgently or often
Other symptoms of ovarian cancer can include;
- Back pain
- Pain during sex
- Upset stomach or heartburn
- Constipation or menstrual changes
What are the Causes Associated with Ovarian Cancer?
There are several factors that can be associated with ovarian cancer or are linked to a higher chance of developing the disease including;
1. Family history:
Women with close relatives who have had earlier cases of breast or ovarian cancer have a higher risk of developing cancer.
Most cases of ovarian cancer occur after the menopause or especially in women aged over 60 to 63 years.
3. Obesity and overweight:
Obesity and overweight seem to increase the risk of developing many cancers one of them is ovarian cancer which is more common in women with a body mass index (BMI) of over than 30.
4. Infertility or fertility treatment:
Fertility drugs or medicines have been linked to a higher risk of cancer, particularly in women who used them for more than one year without becoming pregnant.
5. Birth control:
Using the contraceptive pill for at least 4 to 6 months appears to reduce the risk.
6. Reproductive history:
Women who have had full-term pregnancies, especially before the age of 25 or 26 years, have a lower risk.
What are the Treatments for Ovarian Cancer?
There are several treatments for ovarian cancer after the diagnostic tests have been done. So following are the treatment options one can opt including;
- Targeted therapy
- Hormone therapy
- Radiation therapy [People Also Like:Â Positive Impact of Music Therapy in Depression]
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